Completed Gene Therapy Trials Tracked By U.S. National Library Of Medicine As Of December 2020

Completed Gene Therapy Trials Tracked By U.S. National Library Of Medicine As Of December 2020

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. In a clinical trial, participants receive specific interventions according to the research plan or protocol created by the investigators. … Read more

Risks With CRISPR Gene Editing

Risks With CRISPR Gene Editing

Scientists studying the effects of the potentially game-changing gene-editing tool CRISPR/Cas9 have found it can cause unexpected genetic damage which could lead to dangerous changes in some cells. The findings, published in the journal Nature Biotechnology in 2018, have safety implications for gene therapies that are being developed using CRISPR/Cas9 – a type of molecular … Read more

IPO: AbCellera Biologics

IPO: AbCellera Biologics

Abcellera is an early-stage anti-body based drug discovery company that employs an AI powered platform to develop various therapies. The company has raised approximately $483 million in a recent IPO that was well received by the marketplace. According to Abcellera, the new frontier of technology lies at the interface of computation, engineering and biology – … Read more

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How China Aims To Dominate Precision Medicine And AI

How China Aims To Dominate Precision Medicine And AI

Precision medicine approaches to disease treatment considers individual genetic variation and environment and lifestyle factors. The idea is to tailor treatment and prevention plans to an individual patient. The ability to analyze large data sets and predictive capabilities of artificial intelligence (AI) are the foundation of modern precision medicine. China’s large population and expanding data … Read more

Recent Advances In The Protein Folding Problem

Recent Advances In The Protein Folding Problem

Protein folding in the cell often relies on the help of chaperonins, naturally occurring cellular nanomachines that fold many critical cellular proteins in all human and animal cells. Knowledge of protein folding is important because proteins must assume the correct 3-D structure to function properly. Different classes of chaperones work together to form elaborate cooperative … Read more

What Is Cell Squeeze Technology?

What Is Cell Squeeze Technology?

Cell Squeeze® is a commercial technology designed to manipulate individual cells (ie. a patient’s own cells) through mild perturbation that leaves the cells viable after mechanoporation – or the insertion of a cargo directly into a cell’s cytosol. SQZ Biotech is the sole developer of this technology. One early application consists of a microchip that … Read more

China’s Military Joins Forces With Biotech Companies To Propel COVID Vaccine Efforts

China’s Military Joins Forces With Biotech Companies To Propel COVID Vaccine Efforts

Xi Jinping has called upon the Chinese People’s Liberation Army (PLA) to become a world-class military (世界一流军队) by mid-century. Chinese military modernization has been directed towards learning from and targeting the U.S. military, which is seen as a powerful adversary (强敌). In 2015, China’s President Xi Jinping made science and innovation a key element of … Read more

How To Locate A Gene

How To Locate A Gene

Understanding the link between chromosomes and genes starts with indexing. When you type a query into an Internet search engine, a worldwide web search engine, you can get an answer back in less than a second because a company like Google has already indexed the entire readable Internet. Indexing is also at the core for … Read more

NIH’s 4DN Nucleome Program Targets DNA

NIH’s 4DN Nucleome Program Targets DNA

The goal of the National Insitute of Health’s (NIH) Common Fund’s 4D Nucleome (4DN) program is to study the three-dimensional organization of the nucleus in space and time (the 4th dimension). The nucleus of a cell contains DNA, the genetic “blueprint” that encodes all of the genes a living organism uses to produce proteins needed … Read more