NEWS

aTyr Pharma (ATYR) is developing a new area of biology that re-tunes the immune system by targeting innate immunity at the site of inflammation. The company’s novel tRNA Synthetase Platform produces disease-modifying molecules that promise to knock down important inflammatory and fibrotic markers in a variety of indications, starting with pulmonary sarcoidosis. The company’s near-term … Read more

Creating a valuation estimate for a biotechnology company in Phase 2 trials is as risky as the biotech itself. In the case of Viking Therapeutics (VKTX), I believe the exercise is worth the effort given the rapid adoption of GLP-1 agonists (sometimes referred to as incretins), for the treatment of diabetes and weight loss – … Read more

Acasti Pharma (ACST) is a late-stage specialty biotech developing novel therapies for rare diseases, specifically for those who are underserved or lack treatment options. GTX-104 ACST’s lead program, GTX-104, is a room-temperature stable, IV formulation of nimodipine that targets aneurysmal subarachnoid hemorrhage (aSAH), a life-threatening condition where bleeding occurs over the surface of the brain … Read more

The stock market is designed to appraise the commercial, not the scientific, potential of new medicines. Clinical progression is the only real measure of an early-stage biotech’s commercial potential. Sometimes clinical trial design can cloud the picture of a promising drug candidate – where flaws in read-outs may not be indicative of true value. And … Read more

In the transformative landscape of healthcare, the rise of weight-loss medications such as Ozempic and Wegovy has sparked a cultural and business revolution, challenging our perceptions of obesity and medical treatment. These drugs, originally designed for type 2 diabetes management, have unexpectedly become a beacon for those seeking weight loss solutions, leading to a societal … Read more

In recent groundbreaking research, scientists have discovered that the drug Dulaglutide, commonly used to type 2 diabetes mellitus (T2DM), has shown promising results in reversing depression-like behavior and restoring metabolic balance in the hippocampus of mice subjected to chronic mild stress. This study highlights the intricate link between metabolic disorders and mental health, suggesting a … Read more

In biotech investing, distilling exceptional opportunities from the average (or worse) ventures requires a keen eye on insider activities, financial health, and clinical progress. Beam Therapeutics (BEAM) presents a case that demands caution, with insider stock sales, a substantial accumulated deficit, and limited clinical advancements raising significant concerns. In contrast, Intensity Therapeutics (INTS) is an … Read more

Biotech companies developing GLP-1 agonists for weight loss treatment are being keenly pursued by more mature pharmaceutical companies that have missed the bandwagon so far. This is because use of GLP-1s could increase by 10 – 70 million consumers by 2028, perhaps becoming the largest drug class in history. Reuters reports that the widespread use … Read more

There is a furious pace of innovation, deal flow and drug approvals for the new class of glucagon-like peptide 1 (GLP-1) receptor agonists and the emerging next gen Dual Agonists for the treatment of obesity and weight loss. Among mature pharmaceutics companies, the bandwagon took off when the sleepy backwater of GLP-1s for diabetes treatment … Read more

NeuroBo Pharmaceuticals is a clinical stage drug development company with a focus on weight loss and a GLP-1 Dual Agonist. Its most advanced drug candidate, A-1726, is a novel oxyntomodulin analogue functioning as a GLP1R/GCGR dual agonist for the treatment of obesity. The IND approval is expected soon with Phase 1 trials commencing shortly thereafter. … Read more