CG Oncology Enters Bladder Cancer Therapy Space With IPO

CG Oncology Enters Bladder Cancer Therapy Space With IPO

CG Oncology is a biotech company focused on developing innovative treatments for bladder cancer, particularly non-muscle invasive bladder cancer (NMIBC). Their two main clinical programs involve cretostimogene grenadenorepvec (CG0070), an oncolytic immunotherapy. CG Oncology filed confidentially on October 27, 2023. The company filed publicly this week with the SEC to raise up to $100 million … Read more

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Interview with Lew Bender, President of Intensity Therapeutics

Interview with Lew Bender, President of Intensity Therapeutics

Intensity Therapeutics, Inc. is a clinical-stage biotechnology company applying scientific leadership in the field of localized cancer reduction leading to anti-cancer immune activation. The company’s approach involves the direct injection into tumors of a unique product created from its DfuseRx℠ discovery platform.     Valuation/risk: According to Stifel, Phase 3 valuations are up 33% since … Read more

In Conversation: Matthew McKnight, Chief Commercial Officer, Ginkgo Bioworks

In Conversation: Matthew McKnight, Chief Commercial Officer, Ginkgo Bioworks

Synthetic.com’s publisher and editor, Simons Chase, interviews Matthew McKnight. Matt is the Chief Commercial Officer of Ginkgo Bioworks where he also leads the company’s biosecurity platform, Concentric by Ginkgo. Prior to Ginkgo, Matt spent 7 years as an investor at IndUS Growth Partners and was the President and COO of Decision Resources Group. He has … Read more

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IPO: Immuneering Corp Innovates With Bioinfomatics

IPO: Immuneering Corp Innovates With Bioinfomatics

Immuneering Corp. applies translational bioinformatics to drug development. Its biopharmaceutical therapeutic focus is oncologic and neurologic diseases. The company has more than a decade of experience in translational bioinformatics that it believes allow it to generate superior insights into drug mechanisms of action and patient treatment responses. Immuneering has developed a disease-agnostic platform for human … Read more

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IPO: Absci Corporation Aims For Proteins As Next-Generation Therapeutics

IPO: Absci Corporation Aims For Proteins As Next-Generation Therapeutics

Absci Corp describes itself as an AI-powered integrated drug creation platform. The company creates protein-based drugs (biologics) by unifying biologic drug discovery and cell line development into one process. This places Absci squarely under the umbrella of synthetic biology. The challenge in next-generation biologics is the linear steps needed to screen and select desired molecular … Read more

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IPO: Caribou Biosciences Advances Cell Therapy With CRISPR

IPO: Caribou Biosciences Advances Cell Therapy With CRISPR

Caribou Biosciences is a clinical-stage biopharmaceutical company innovating in next-generation, genome-edited cell therapies. Its CRISPR hybrid RNA-DNA (chRDNA) guide technology has demonstrated superior specificity and high efficiency in preclinical studies, and, according to the company, has the potential to generate gene and cell therapies in oncology and in therapeutic areas beyond oncology, including immune cell … Read more

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IPO: Verve Therapeutics Takes On Cardiovascular Disease Using Gene Editing

IPO: Verve Therapeutics Takes On Cardiovascular Disease Using Gene Editing

Verve Therapeutics, a biotech company innovating new approaches to the care of cardiovascular disease with single-course gene editing medicines, announced terms for its $201 million IPO on today. Insiders Wellington Management and Casdin Capital and new investor Fidelity have indicated an interest in purchasing up to an aggregate $75 million worth of shares in the … Read more

IPO: Zymergen’s Valuation Soars to $8 Billion On Market Debut

IPO: Zymergen’s Valuation Soars to $8 Billion On Market Debut

Zymergen, an Emeryville, California–based synthetic biotechnology firm, recently raised $500 million in an initial public offering (IPO) of stock on the NASDAQ exchange that values the 8-year-old company at over $3 billion. Four months ago, Zymergen launched its first product, Hyaline, a polymer film for electronic displays that it developed with Sumitomo Chemical. Zymergen makes … Read more

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World’s Biggest Growth Investors Pool Assets To SPAC & PIPE Ginko Bioworks

World’s Biggest Growth Investors Pool Assets To SPAC & PIPE Ginko Bioworks

Ginkgo Bioworks, Inc.’s (“Ginkgo”) founders have been working together for nearly twenty years since they first met at MIT. They launched Ginkgo in 2008 with the consistent goal of developing a platform that makes cell programming easier for their customers and partners. Ginkgo’s platform leverages advanced robotic automation, proprietary software, and data analytics to continuously … Read more

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