Biologically Inspired Engineering, synbio, synthetic biology, crispr
Staff 
GLP-1’s have emerged as a powerful agent in the treatment of population-level disease states. And there appears to be some hidden depths in regard to their potential to address serious conditions upstream of their initial indications. Here are two combinations that show promise, one inside a company and another in the laboratory that addresses neurodegeneration. … Read more
Aardvark Therapeutics, a San Diego-based biotech company, is on track for an initial public offering (IPO) this summer. The company is developing a weight loss pill, ARD-101, that has shown promise in early-stage trials. ARD-101 works differently from other weight loss drugs by targeting two gut hormones, GLP-1 and CCK, which could potentially reduce side … Read more
In the transformative landscape of healthcare, the rise of weight-loss medications such as Ozempic and Wegovy has sparked a cultural and business revolution, challenging our perceptions of obesity and medical treatment. These drugs, originally designed for type 2 diabetes management, have unexpectedly become a beacon for those seeking weight loss solutions, leading to a societal … Read more
Our immune system is complex beyond comprehension. It acts as a vigilant guard, constantly patrolling for and eliminating threats like viruses, bacteria, and even abnormal cells that could turn cancerous. Cancer is a cunning adversary. New research from a collaborative effort by scientists at the Massachusetts Institute of Technology (MIT), Dana-Farber Cancer Institute, Harvard Medical … Read more
Immix Biopharma (IMMX) is CART-T cell therapy company targeting oncology and immune-dysregulated disease. Immix’s subsidiary Nexcella (94% owned) focuses a CAR-T therapy, NXC-201, which is in clinical trials for the treatment of multiple myeloma and AL amyloidosis (ALA). The company’s other promising therapy, IMX-110, is being investigated in a Phase 1b/2a study for the treatment … Read more
U.S. pharmaceutical companies Moderna and Merck say a clinical trial for an experimental Moderna mRNA vaccine used in combination with the Merck cancer therapy drug Keytruda reduced the chance of recurrence or death from melanoma by nearly 50%. “As we continue to follow participants in the KEYNOTE-942/mRNA-4157-P201 study, we are excited to see such a … Read more
CG Oncology is a biotech company focused on developing innovative treatments for bladder cancer, particularly non-muscle invasive bladder cancer (NMIBC). Their two main clinical programs involve cretostimogene grenadenorepvec (CG0070), an oncolytic immunotherapy. CG Oncology filed confidentially on October 27, 2023. The company filed publicly this week with the SEC to raise up to $100 million … Read more
Ohalo Genetics is dedicated to accelerating the evolution of crops to create more efficient and sustainable agriculture. They use innovative plant genetic technologies to improve various aspects of crops, including: Yield: They aim to increase crop yields to meet the growing demand for food from a world population that is expected to reach 10 billion … Read more
Google Cloud recently announced two new AI-powered life sciences solutions to accelerate drug discovery and precision medicine for biotech companies, pharmaceutical firms, and public sector organizations. The Target and Lead Identification Suite helps researchers better identify the function of amino acids and predict the structure of proteins; and the Multiomics Suite accelerates the discovery and … Read more
Earlier this year, a Jefferies analyst quantified the market downturn in the biotechnology sector and came up with a number: 128 companies were trading at a market cap smaller than the cash they have on hand, representing 25% share. This rivals the severity of 2008-2009 period, where 15-20% of the industry was trading below cash. … Read more