Pfizer Will Collaborate With Beam Therapeutics For In Vivo Base Editing

Pfizer Will Collaborate With Beam Therapeutics For In Vivo Base Editing

Today, Pfizer Inc. and Beam Therapeutics Inc., a biotechnology company developing precision genetic medicines through base editing, announced an exclusive four-year research collaboration focused on in vivo base editing programs for three targets for rare genetic diseases of the liver, muscle and central nervous system. Investors should note Pfizer will pay Beam $300 million up … Read more

Mayo Clinic Reports mRNA Progress In Cancer Treatment

Mayo Clinic Reports mRNA Progress In Cancer Treatment

Mayo Clinic research shows treatment improvement by adding messenger RNA, or mRNA therapy improves the response to cancer immunotherapy in patients who weren’t responding to the treatment. Immunotherapy uses the body’s immune system to prevent, control and eliminate cancer. The study is published in Cancer Immunology Research, a journal of the American Association for Cancer … Read more

Arc Institute Emerges After Two Years Of Development

Arc Institute Emerges After Two Years Of Development

Arc Institute is a nonprofit research organization headquartered in Palo Alto, California. Arc is an independent institute that operates in collaboration with Stanford University, the University of California, Berkeley, and the University of California, San Francisco. According to Arc, biomedical innovation in areas such as mRNA technology, gene editing, and cell therapies suggest that historic … Read more

Mapping The Protein Machinery of Cancer Cells

Mapping The Protein Machinery of Cancer Cells

Proteins are often called the workhorses of cells, the machinery that makes cells go. They act as key players in the many chemical reactions constantly occurring in cells, collect cellular garbage, provide structure, repair damaged DNA, and much more. But individual proteins rarely act on their own. Instead, like molecular LEGO bricks, they join together … Read more

Strand Therapeutics Wins NIH CAR-T Cell Immunotherapy Contract

Strand Therapeutics Wins NIH CAR-T Cell Immunotherapy Contract

Strand Therapeutics, a privately held biotech company developing next-generation, programmable mRNA therapeutics beyond vaccines, announced last week that the company was awarded a Phase I Small Business Innovation Research (SBIR) contract from the National Cancer Institute (NCI) of the National Institutes of Health (NIH) to develop an off-the-shelf chimeric antigen receptor T cell (CAR-T) immunotherapy … Read more

This Study Seeks to Prevent Cancer By Targeting Genetic Risk For Ovarian Cancer

This Study Seeks to Prevent Cancer By Targeting Genetic Risk For Ovarian Cancer

Researchers in gynecologic oncology have begun testing a promising surgery for premenopausal women at high genetic risk for ovarian cancer that avoids early menopause and may prevent these malignancies from developing. Studies have shown that most ovarian cancers actually begin to grow from cancer cells that developed in the fallopian tubes. This trial is testing … Read more

This Scientist Focuses On How Cells Record Trauma

This Scientist Focuses On How Cells Record Trauma

Barbara Engelhardt, PhD, builds machine-learning models and statistical tools to make use of data (scientific experiments, longitudinal studies, clinical trials, and hospital records) and find ways to better understand, and even prevent, disease. She is now joining Gladstone Institutes as a senior investigator. Engelhardt is also a full professor at Princeton University, on leave this … Read more

NIH To Fund $185 Million For Research Into Human Genome Functions

NIH To Fund $185 Million For Research Into Human Genome Functions

The National Institutes of Health (NIH) is providing approximately $185 million over five years to the Impact of Genomic Variation on Function (IGVF) consortium, initiated and funded by NIH’s National Human Genome Research Institute (NHGRI). NHGRI will fund 25 awards across 30 U.S. research sites. IGVF consortium investigators will work to understand how genomic variation … Read more