NeuroBo Pharmaceuticals is a clinical stage drug development company with a focus on weight loss and a GLP-1 Dual Agonist.
Its most advanced drug candidate, A-1726, is a novel oxyntomodulin analogue functioning as a GLP1R/GCGR dual agonist for the treatment of obesity. The IND approval is expected soon with Phase 1 trials commencing shortly thereafter. Its other therapy is DA-124, a novel G-Protein-Coupled Receptor 119 (GPR119) agonist with development optionality as a standalone and/or combination therapy for both MASH and T2DM. Its Phase 2a first patient was dosed September 15, 2023 with interim data due in 1H 2024. Full results due in 2H 2024. The company is backed by strategic partner and major shareholder, Dong-A ST. DA-1726 outperformed Semaglutide (WEGOVY), a GLP-1 agonist, in mouse models of obesity. The company has a negative EV.
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