WARF Dive: Synthetic Ligands Capable of Strongly Inhibiting or Inducing Quorum Sensing in Bacteria

WARF Dive: Synthetic Ligands Capable of Strongly Inhibiting or Inducing Quorum Sensing in Bacteria

The Wisconsin Alumni Research Foundation (WARF) is seeking commercial partners interested in developing a powerful new class of chemical probes that are capable of strongly inhibiting or inducing quorum sensing. Quorum sensing is a process used by some bacteria to coordinate behavior based on local population density. To communicate, bacteria release signaling molecules, including low … Read more

NASA’s Plans Involving Synthetic Biology

NASA’s Plans Involving Synthetic Biology

NASA is investigating two potential applications of synthetic biology—one to advance nutrition and one to increase in-space manufacturing capabilities. Astronauts aboard the International Space Station receive regular resupply shipments from Earth, providing them with nutritious food during their expeditions. Future astronauts on the journey to Mars will be much farther away, outside the reach of … Read more

Entrepreneurs Accelerate The Search for Early Detection of Pancreatic Cancer

Entrepreneurs Accelerate The Search for Early Detection of Pancreatic Cancer

Scientists have identified more than 1,000 potential new biomarkers for cancer that they hope will aid in the early detection of many of these complex diseases, including one of the most challenging, pancreatic cancer. In the alternate universe of reward-sensitive entrepreneurs, Jo Bhakdi has rolled out a new liquid biopsy product that detects potentially cancerous … Read more

FDA Approves First KRAS Therapy for Lung Cancer Mutation Previously Considered Undruggable

Today, the U.S. Food and Drug Administration approved Lumakras (sotorasib) as the first treatment for adult patients with non-small cell lung cancer whose tumors have a specific type of genetic mutation called KRAS G12C and who have received at least one prior systemic therapy. This is the first approved targeted therapy for tumors with any … Read more